An Improved Method of Arachidonic Acid Production by Mortierella alpina
نویسندگان
چکیده
منابع مشابه
Arachidonic acid production by Mortierella alpina using raw crop materials.
BACKGROUND Arachidonic acid (ARA) is one of the three essential fatty acids, and it is important for human body to keep healthy and is widely used. At present, expensive materials such as glucose and yeast extract are generally reported to be optimal for ARA production. A new cost-effective fermentation process including cheaper material for ARA production is of great significance. METHODS Fe...
متن کاملStatistical Optimization of Arachidonic Acid Production by Mortierella alpina CBS 754.68 in Submerged Fermentation
Arachidonic acid is an essential fatty acid in human nutrition. In the present study, production of arachidonicacid by Mortierella alpina CBS 754.68 was evaluated in submerged fermentation. The fermentation variableswere selected in accordance with the Plackett-Burman (PB) design and further optimized via response surface methodology (RSM). Five significant variables, namely glucose...
متن کاملStatistical optimization of arachidonic acid production by Mortierella alpina CBS 754.68 in submerged fermentation
Arachidonic acid is an essential fatty acid in human nutrition. In the present study, production of arachidonic acid by Mortierella alpina CBS 754.68 was evaluated in submerged fermentation. The fermentation variables were selected in accordance with the PlackettBurman (PB) design and further optimized via response surface methodology (RSM). Five significant variables, namely glucose, yeast ext...
متن کاملMetabolic engineering of Mortierella alpina for arachidonic acid production with glycerol as carbon source
BACKGROUND Although some microorganisms can convert glycerol into valuable products such as polyunsaturated fatty acids, the yields are relative low due primarily to an inefficient assimilation of glycerol. Mortierella alpina is an oleaginous fungus which preferentially uses glucose over glycerol as the carbon source for fatty acid synthesis. RESULTS In the present study, we metabolically eng...
متن کاملAn Online Respiratory Quotient-Feedback Strategy of Feeding Yeast Extract for Efficient Arachidonic Acid Production by Mortierella alpina
Mortierella alpina (M. alpina) is well known for arachidonic acid (ARA) production. However, low efficiency and unstableness are long existed problems for industrial production of ARA by M. alpina due to the lack of online regulations. The aim of the present work is to develop an online-regulation strategy for efficient and stable ARA production in industry. The strategy was developed in 50 L f...
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ژورنال
عنوان ژورنال: Journal of Japan Oil Chemists' Society
سال: 1987
ISSN: 1884-2003
DOI: 10.5650/jos1956.36.328